一名喝農藥自殺的43歲男性個案,被送至本院急診時,意識不清並表現出毒蕈樣(muscarinic)及菸鹼樣(nicotinic)的中毒症狀,此外,患者乙醯膽鹼酯 活性降低至188 U/L。在確立診斷為有機磷中毒後,即施以洗胃及活性碳治療,而後給予atropine及pralidoxime,病人入院後陸續併發心搏過慢及吸入性肺炎。住院11天後,有機磷中毒症狀消失及吸入性肺炎獲得控制,且乙醯膽鹼酯 值回復至1,000 U/L,情況穩定後出院。
A case of a 43-year-old man with acute ingestion of Fenthion—an anticholinesterase insecticide—is reported here. Upon arrival in the Emergency Department, not only were patient’s decreased consciousness and the toxic symptoms of organophosphate intoxication observed, but a very low level of acetylcholinesterase activity (188 U/L) was also measured. After the diagnosis of organophosphate intoxication, the patient was gastric lavaged, and then treated with atropine and pralidoxime. During hospitalization, the patient suffered from complications of bradycardia and aspiration pneumonia. Because aspiration pneumonia was well controlled, the acetylcholinesterase activity was raised to 1,000 U/L, and the toxic symptoms disappeared—the patient was discharged after 11 days.