本文係報告一位46 歲腎功能不佳之男性病人於住院期間連續使用labetalol 治療高血壓而產生高血鉀,於停藥後血鉀恢復正常的案例報告。輕度高血鉀通常沒有症狀且容易處置,然而血鉀濃度≥ 7.0 mEq/L 的嚴重高血鉀,臨床表現包括肌肉無力或麻痺、心肌傳導異常及心律不整,可能導致病患死亡。藉此案例報告提醒醫療人員應提高藥物可能造成高血鉀的警覺性,以減少病人因藥物導致不良反應而使延長住院天數,甚至併發其他健康危害。
A 46-year-old male patient with chronic kidney disease was admitted to our hospital for the treatment of generalized weakness and labetalol was given for his hypertension. He developed hyperkalemia during hospitalization and returned to normal after stopping the labetalol. Although mild hyperkalemia is usually symptom-free and easy to handle, however patients with a potassium concentration of ≥ 7.0 mEq/L could develop clinical manifestations including muscle weakness or paralysis, abnormal myocardial conduction, and arrhythmia which may further lead to death. This case report reminds all healthcare professionals to increase the alertness of drugs that may cause hyperkalemia, so as not to lengthen the hospital stays and avoid other health hazards caused by drug-induced adverse events.