Objective: Heart failure (HF) is a high-risk group for drug-related problems. An interprofessional integrated care model should be developed. This study analyzed the effectiveness of pharmacist participation in the integrated care model of post-acute care HF (HF-PAC).
Methods: This was a prospective study. The intervention consisted of pharmaceutical services including assessment of guideline-directed medical therapy, prescription appropriateness, and medication knowledge. Medication education, adverse drug reaction (ADR), and measurement of left ventricular ejection fraction (LVEF) were also provided.
Results: A total of 61 cases were included in this study. Six months after discharge, 87.3% still used angiotension-converting enzyme inhibitors/angiotension II receptor blockers/angiotensin receptor-neprilysin inhibitor, and 80.9% used β-blockers. A total of 18 prescriptions were classified as “severe and significant”, and this mainly occurred in the stage before discharge. In these cases, the pharmacist’s recommendations were 100%. The patient’s medication knowledge score increased by 2.7 points after medication education (p < 0.05). A total of 6 cases of ADR occurred. The symptoms improved after withdrawing or changing the medication. Six months after discharge, the overall LVEF increased by an average of 12.0% (p < 0.05), and the number of patients with LVEF ≥ 40% increased from 8 to 30.
Conclusions: Pharmacist participation in the HF-PAC team prevented inappropriate prescriptions and strengthened medication education. The pharmacists not only improved patients’ medication knowledge but also increased medical adherence.
Summited for publication: 2020.12.7; Accepted for publication: 2021.3.16