Cyclosporine（CyA）與tacrolimus（FK506）是目前器官移植所需免疫抑制劑的兩大主流，藥理機轉與藥物不良反應相似。CyA引起的多毛症在許多文獻資料已獲證實，但FK506導致禿髮不良反應的案例報導並不多。本案例是報告一名腎臟移植病患在服用FK506四個月後發生禿髮現象，而隨著劑量的調降又恢復頭髮生長的經過，同時也強調藥師對腎移植病患用藥教育與付出關心的重要性，尤其對於已發生藥物不良反應的病患應給予支持與鼓勵。

Cyclosporine (CyA) and tacrolimus (FK506) are the main immunosuppressive agents in the current solid organ transplantations, and their pharmacological effects and adverse effects are similar. The adverse effects of hirsutism in the CyA has already been reported and documented. The case report of FK506 induced alopecia is very rare. We reported case of alopecia induced by FK506 after renal transplantation and hair regrowth after the dosage were decreased. Besides, we emphasize the importance of role of pharmacists intervention regarding drug education for transplanted patients, especially for those with adverse drug reactions.