根據許多臨床研究證據顯示,給予適當的急性心肌梗塞病人特定的藥物治療如aspirin, beta-blockers, ACEIs, 以及 statins,可以有效的改善死亡率及致疾病率,但是在知識與臨床實際應用之間仍存有落差。
為了要調查某醫學中心急性心肌梗塞病人的藥物治療品質指標達成率,我們根據急性心肌梗塞病人的臨床治療準則,針對藥物治療部份選取 7 項的治療品質指標。對於所有在 2002 年1 月1 日至2002 年3 月31 日這期間,根據國際疾病分類碼,出院的主要診斷為急性心肌梗塞的病人,進行回溯性的病歷回顧。
病人入院 24 小時內使用治療品質指標藥物的比例分別為 aspirin 99%beta-blockers 38% 以及ACEIs 59%;病人出院前使用治療品質指標藥物的比例分別為aspirin 95%,beta-blockers 51%,ACEIs 72% 及statins 38%。
在調查過急性心肌梗塞病人的各項藥物治療品質指標達成率後,可以針對未達理想之藥物使用比例,提出改善的方案,以期有助於未來急性心肌梗塞病人藥物治療品質的增進。
A lot of evidence from clinical research has demonstrated the benefit of aspirin, beta-blockers, ACEis, and statins for appropriate patients with AMI in lowering mortality and morbility. There is still a gap between knowledge and its application to clinical care.
In order to investigate the percentage of patients receiving appropriate pharmacologic therapy as defined by 7 quality-of-care indicators derived from clinical practice guidelines. We retrospectively reviewed all medical records of patients discharged with a principal diagnosis of AMI between January I, 2002, and March 31,2002.
In cohorts of patient without contraindication, 99% received aspirin, 38%received beta-blockers, and 59% received ACEis within 24 hours of hospital arrival;95% received aspirin, 51 % received beta-blockers, 72% received ACEis, and 38%received statins at discharge.
Action regarding to each underused drug should to taken to improve the quality of phannacologic therapy for patient with AMI.