Daunorubicin, one of anthracyclines, is used in the treatment of hematological cancer. Besides general side effects of chemotherapy, including nausea, vomiting, bone marrow suppression, hair loss and oral ulcers, there are some troublesome side effects -- cardiac toxicities. Anthracyclines-induced cardiac toxicities could be divided into acute and chronic types. Acute cardiac toxicities are rare and reversible. Chronic cardiac toxicities are more often than acute cardiac toxicities, dose-limited and irreversible. This case report was about daunorubicin-induced acute cardiac toxicity after 2 weeks of doxorubicin therapy. The adverse effects relieved after intensive care. Reminding clinical care-givers should monitor closely and be more observant about the adverse effects when administrating anthracyclines by this case report.