週邊動脈疾病 (peripheral arterial disease, PAD) 是一種因動脈狹窄而減少血流至肢體的循環異常疾病，常見於老年人。有PAD 的人可能會增加全因死亡率 (all-cause mortality)，尤其是有肢體功能表現退化的人會提高日後行動喪失的風險。雖然處理病人PAD 的方法包括運動、藥物介入、或手術循環重建，然而在疾病初期僅少數病人有出現典型的跛行 (claudication)，使得運動成為預防PAD 的好方法而避免此疾病惡化與改善預後。
強度與限制: 運動的時機、優缺點、與機轉在本文均有充分的提及和討論，此結果可應用於任何潛在患者的預防或治療PAD。不過，動作 (motion) 的範圍或角度，以及運動的速度之相關資訊是比較不足的，進一步研究來釐清這些細節是有必要的。

Peripheral arterial disease (PAD), a circulatory disorder where narrowed arteries decrease blood to limbs, is commonly seen in old people. Individuals with PAD may increase risk for all-cause mortality, especially those with declining functional performance being at greater risk for later mobility loss. Although management for patients with PAD include exercises, pharmacological intervention, or surgical revascularization, only few individuals have classic claudication at the initial stage making exercise a good option for preventive
management to avoid progression of PAD, and improve the patients’ prognosis. Strengths and limitations:Timing, and pros and cons of exercises, in addition to mechanisms, are appropriately mentioned and discussed in this article which can be applied to any potential individual for prevention or management of PAD. However,information related to range of motion and speed of exercises are insufficient. Further studies are needed in order to clarify these details.