登革熱在臺灣是重要的公共衛生問題，發生過幾次爆發流行。臺灣的病例對照研究，60 歲以上長者及糖尿病患者是登革出血熱死亡的獨立預測因子。另一篇國內的世代研究顯示，器官衰竭與凝血障礙是登革熱住院病患死亡的獨立預測因子。本文案例為69 歲的男性再次感染登革熱，出現嚴重血小板低下併有肝功能異常，是出血的高危險群；且疑似因感染登革熱引發胰臟炎、膽囊炎、腎臟損傷，為少見但致命的併發症，目前臨床治療經驗有限。藉由文獻回顧與案例報告，探討登革熱引發器官衰竭的可能病症、臨床評估事項與治療方法，以增進疾病照護的完整。

Dengue fever is an important public health problem in Taiwan and a few epidemics have occurred. A case-control study in Taiwan found that elderly people aged 60 years and above and diabetic patients were independent predictors for death due to dengue hemorrhagic fever. Another Taiwanese cohort study found that organ failure and coagulation disorders were independent predictors for death in hospitalized dengue fever patients. In this case report, a 69-year-old male was re-infected with dengue fever and presented with severe thrombocytopenia accompanied by liver function abnormalities belonging to the high risk population for hemorrhage. He also presented rarely seen but fatal complications such as pancreatitis, cholecystitis, and kidney damage that were suspected to be caused by dengue fever, of which current clinical therapy experiences are limited. Based on literature review and this case report, we examined the possible complications of organ failure caused by dengue fever, clinical assessment items, and therapeutic measures, so as to enhance the completeness of patient care.