睡眠與癲癇有相互的影響。有良好睡眠的質及量對於記憶鞏固及突觸可塑性是必須的，而癲癇會加重睡眠結構破壞和睡眠障礙的嚴重程度。抗癲癇用藥通常會影響睡眠的品質及結構，本文主要探討抗癲癇用藥對於睡眠的影響，希望有助於臨床上抗癲癇用藥的選擇。

Sleep and epilepsy have a reciprocal relationship. Good quantity and quality sleep is required for memory consolidation and synaptic plasticity. Epilepsy can worsen sleep architecture and severity of sleep disorders. Antiepileptic drugs (AEDs) that are commonly used for seizure treatment affect sleep quality and architecture. It is important for clinicians to understand the proclivity of a specific AED to affect the quality of sleep in order to guide epilepsy therapy.