社團法人臺灣臨床藥學會

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【案例報告】疑似因顯影劑引起之腎病變案例報告
Contrast medium-induced nephropathy
Contrast-Induced Nephropathy (CIN),nephropathy
蔡芳佩Fang-Pei Tsai* 、吳大圩,Ta-Wei Wu
1佛教慈濟綜合醫院台北分院 藥劑科
顯影劑引起的腎病變可能導致住院時間延長、暫時性的洗腎和死亡率增加,而且CIN是導致住院病患急性腎損傷的主要原因之ㄧ,治療方法有限,一般為支持療法,因此主要的目標是找出使用顯影劑有引起腎病變風險的病人和以經證實的預防方法來改善病患的結果。本案例為高齡且有貧血和肺水腫病史,在沒有其他引起腎病變之因素下,懷疑顯影劑為引起腎病變之主因,希望能藉此病例提醒大家注意,以避免類似的情形發生。

Contract induced nephropathy (CIN) is a significant clinical problem which not only prolongs hospital stay, but also increases the requirement of transient dialysis, it is also related to greater mortality. Moreover, CIN is the main leading cause of acute reduction in renal function in hospitalized patients. Treatment options for CIN are generally supportive and limited. Therefore, the main goal is to identify patients at risk of CIN and to improve patient outcomes by applying preventative measures with evidence base.
The case is a 84-year-old male with a medical history of anemia and pulmonary edema. There seemed  no  other contributing factor  with  the  exception of  contrast  medium for  the  induction of nephropathy. In the light of this event, it is hoped to raise some attention for avoidance of repeating such incidence.
 
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