社團法人臺灣臨床藥學會

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【案例報告】腦動脈瘤破裂之案例報告
Ruptured Cerebral Aneurysms: Case Reports
動脈瘤破裂、血管痙攣、Nimodipine、Cerebral Aneurysm Rupture, Cerebral Vasospasm, Nimodipine
蘇玉惠Yu-Hui Su*1 、楊璦瑜Ai-Yu Yang1 、郭震羣Chen-Chun Kuo1
1高雄醫學大學附設中和紀念醫院藥劑部
自發性蜘蛛膜下腔出血 (spontaneous subarachnoid hemorrhage) 最常見原因是腦動脈瘤破裂,約占所有案例的85%,病患平均發病年齡在55 歲。腦血管痙攣 (cerebral vasospasm) 和再出血 (rebleeding), 會導致動脈瘤蜘蛛膜下腔出血 (aneurysmal subarachnoid hemorrhage) 病人的失能和死亡。因此,儘早進行動脈瘤處置和藥物介入以預防腦血管痙攣應是首要步驟。本案例報告乃對於腦動脈瘤破裂之認知,與nimodipine 之治療及應用作探討。

The most common cause of spontaneous subarachnoid hemorrhage is cerebral aneurysm rupture which accounts for around 85% of patients. The average incident age of such patients is 55 years. Cerebral vasospasm and rebleeding will lead to disability and death for those with aneurysmal subarachnoid hemorrhage. Therefore, initial management should focus on early aneurysm intervention and drug treatment to prevent vasospasm. This case report discusses the management of cerebral aneurysm rupture and the application of nimodipine.
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