社團法人臺灣臨床藥學會

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【病例報告】疑似Methylprednisolone引起的過敏性休克—案例報告
Methylprednisolone-Induced Anaphylactic Shock — a Case Report
methylprednisolone、anaphylaxis、allergic、hypersensitivity、過敏性休克、methylprednisolone, anaphylaxis, allergic, hypersensitivity, anaphylactic shock
林慧娟Hui-Chuan Lin 、張其純Chi-Chun Chang
1嘉義基督教醫院 藥劑科
此病例是一位因車禍導致脊髓受傷的病人,為抑制脊髓損傷後脂肪的過氧化及抑制損傷引發的連鎖效應以促進恢復,在使用類固醇methylprednisolone後產生過敏性休克的反應。使用類固醇在少數的病人身上有可能會發生過敏的反應,甚至會威脅病人的生命。在發生過敏性休克時,若能立刻給予適當的處置則可減少進一步的傷害。

The patient was a victim of a traffic accident that resulted in spinal cord injury (SCI). Methylprednisolone was given to the patient to inhibit post-SCI lipid peroxidation and the subsequent, injury-induced, degenerative cascade. However, following injection of methylprednisolone, the patient suffered from anaphylaxis. Some patients experience an allergic reaction towards corticosteroids, a reaction that may in some cases be fatal. When a patient experiences anaphylactic shock, therefore, providing them with the appropriate treatment promptly can keep the harm suffered to a minimum.
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