目的：在靜脈營養中脂肪乳劑常被用來做為熱量及必需脂肪酸的來源。然而，曾有研究指出使用人造的脂肪乳劑可能會導致血清中三酸甘油酯（TG）的濃度升高。因此，本研究目的在了解本院於脂肪乳劑使用前、使用後監測TG的執行率，並進一步分析病患接受脂肪乳劑輸注後，對血清三酸甘油酯濃度變化之影響。
方法：藉某醫學中心現有之脂肪乳劑品項10%及20% Lipofundin MCT/LCT之使用，以回溯性分析2007年7月1日至2008年6月30日曾有使用Lipofundin的住院病患病歷，將年齡、體重、科別、有無同時併用碳水化合物輸液、Lipofundin的使用天數、使用劑量及Lipofundin使用前後病人的TG檢測值加以整理紀錄後，再進一步分析輸注Lipofundin對血清三酸甘油酯濃度變化之影響。
結果：回溯此一年期間有630人使用Lipofundin，排除小兒科、小兒外科病人後，共收案578位進行分析。所有病患使用Lipofundin的劑量皆小於文獻最大建議量。共有108人（18.7%）在使用Lipofundin前三個月的時間內曾監測TG。Lipofundin使用後有64人（11.1%）監測TG：監測TG兩次以上的有29人，其中11人的TG值攀升而出現高三酸甘油酯血症。
結論：研究顯示院內實際上於脂肪乳劑使用前、使用後監測TG的執行率偏低，其中38%的個案併發高三酸甘油酯血症。藥師審核脂肪乳劑處方時，應加強核對或追蹤病人的血清三酸甘油酯濃度，以確保病人的用藥安全。

Objective: Intravenous fat emulsion (IVF) is commonly used in parenteral nutrition. It is recognized as a source of energy and essential fatty acid. However, the artificial fat emulsions have been reported to raise the serum concentration of triglyceride (TG). Therefore, the aim of this study is to evaluate the impact of IVF on serum TG concentration and to investigate the execution rate of TG monitoring before and after uses. 
Methods: Ten or twenty percent Lipofundin containing equal parts of medium-and long-chain triglycerides were used in this study. We retrospectively reviewed the usage of Lipofundin and the serum TG levels monitored from Jul.1.2007 to Jun.30.2008. 
Results: In this study period, 630 patients received Lipofundin administration and there were prescriptions for 578 patients reviewed after exclusion. The dosages of Lipofundin were all within the normal range. The sampling rate of TG concentration prior and post administration of Lipofundin were 18.7% and 11.1% respectively. The incidence of hypertriglyceridemia was 38%. 
Conclusion: This study shows that the execution rate of TG monitoring was insufficient. For ensuring patient safety in IVF uses, pharmacists have to aggressively educate medical staff about the significance of the routine TG surveillance.